Resources for Lead Optimization

Lead Optimization

To address the challenges of discovery and development for novel molecules, Eurofins Discovery regularly invests in people, technology, and innovation to build a global, integrated organization that offers valuable knowledge and experience to progress your drug discovery programs.
 
Whether you are investigating small molecules or biotherapeutics, Eurofins Discovery is with you every step of the way in translational study design and services to quickly deliver a promising, robust pre-clinical candidate. Our expertise in all major target classes and therapeutic areas guide understanding in mode-of-action (MOA), target-based and phenotypic profiling, in vitro secondary and safety pharmacology and pharmacokinetic/pharmacodynamics (PK/PD) assessment that will inform your molecules’ pathway engagement in human biological systems, potency, and selectivity.

Key Areas

Your organization may have a novel target, pathway, or phenotype of interest, or a new approach in a well-explored area—along with challenges in program implementation.

Discover comprehensive protein production services, leveraging bacterial, insect, and mammalian expression systems for high-quality, scalable protein.

Gain an early understanding of your lead compounds’ drug-like properties of absorption, distribution, metabolism, and excretion (ADME), as well as potential toxicities, from our growing portfolio of over 600 assays.

Develop Safer Preclinical Candidates with Industry-leading, Reliable and Robust In Vitro Safety Assays and Panels

Phenotypic drug discovery gives you a head start on clinical success with translationally relevant biomarkers as functional readouts for insights on mechanism of action, efficacy, and toxicity assessments.

Our technical experts and partner lab can customize in vivo testing for your specific study design or disease model, creating an efficient process that propels you closer to the clinic.