Biological Information

Family:

GPCR

Sub Family:

Prostanoid

Class:

Class A

Protein Name:

EP3

Uniprot Number:

P43115

Protein Aliases:

PGE receptor EP3 subtype / PGE2-R / Prostanoid EP3 receptor / PTGER3

Organism:

Human

Construct Details:

Recombinant

Cell Type:

Chem-1

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Functional Mode:

Agonist

Detection Method:

Fluorimetry

Measured Response:

Fluorescence

Testing Information

Incubation:

RT

Control Activator:

Prostaglandin E2

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 70 µL of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM finµL testing. 2) Dose Response: 90 µL of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

16

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

5280360

Name

Prostaglandin E2

Measurement

1.8nM - EC50

PubChem ID

91746214

Name

Iloprost

Measurement

260nM - EC50

PubChem ID

24724621

Name

sulprostone

Measurement

4.5nM - EC50

Clinical Relevance

Therapeutic Area:

Gastroenterology

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

RELATED SOLUTIONS

Item: 4331
Item: G305